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The reported advantages of using nanomaterials over conventional size constructs for fabricating functional scaffold/growth-factor delivery systems are based on their increased surface area for growth factor adsorption and cell attachment. Recent reports on human platelet lysate suggest that it is a reliable source of osteogenic growth factors and is capable of potentiating robust increases in the activity of osteogenic cells To gain more insight on the advantages of fabricating nanomaterials with growth factors, it is important to determine the amount of growth factor content being released and whether or not it is still biologically active. Treating nanomaterials with growth factors may give rise to novel regenerative micro/nano-environments that could be useful for bone tissue engineering applications. © 2016 Dziak R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Andrew Barone Adam Morrell and Rosemary Dziak* Nano calcium sulfate Human platelet lysate Platelet-derived growth factor Mesenchymal stem cells Human osteoblastic cells 2016-07-02T12:46:43+05:30 2016-07-02T12:46:44+05:30 2016-07-02T12:46:44+05:30 5 Adobe InDesign CS6 (Windows) uuid:7102e119-5f83-4b07-a523-ab14166b0047 xmp.did:FE00469DB0C7E411AEB789ACBE3823B3 xmp.id:E583B3E62440E611A25CD65F6385D73C proof:pdf xmp.iid:E483B3E62440E611A25CD65F6385D73C xmp.did:F2BC7D9EC6C7E411AEB789ACBE3823B3 xmp.did:FE00469DB0C7E411AEB789ACBE3823B3 default converted from application/x-indesign to application/pdf Adobe InDesign CS6 (Windows) / 2016-07-02T12:46:43+05:30 Citation: Barone A, Morrell A, Dziak R (2016) Fabrication and Characterization of NanoCalciumSulfate and Human Platelet Lysate as a GrowthFactor Delivery System. Int J Dent Oral Health2(4): http://dx.doi.org/10.16966/2378-7090.172 Rosemary Dziak, Department of Oral Biology, University at Buffalo,State University of New York, Buffalo, NY, USA, 14214; Tel: 716-829-3827; Fax: 716-829-3942; E-mail: rdziak@buffalo.edu Adobe PDF Library 10.0.1 False endstream endobj 288 0 obj <> endobj xref 0 929 0000000000 65535 f 0000239516 00000 n 0000240092 00000 n 0000240115 00000 n 0000240249 00000 n 0000249941 00000 n 0000250054 00000 n 0000281958 00000 n 0000281993 00000 n 0000282068 00000 n 0000282348 00000 n 0000282433 00000 n 0000282493 00000 n 0000283194 00000 n 0000283219 00000 n 0000283354 00000 n 0000324777 00000 n 0000325096 00000 n 0000325415 00000 n 0000357320 00000 n 0000357357 00000 n 0000389262 00000 n 0000389299 00000 n 0000421204 00000 n 0000421241 00000 n 0000421317 00000 n 0000421595 00000 n 0000421671 00000 n 0000421950 00000 n 0000422026 00000 n 0000422308 00000 n 0000422393 00000 n 0000422453 00000 n 0000422917 00000 n 0000423526 00000 n 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65535 f 0000000000 65535 f trailer <]>> startxref 116 %%EOF 287 0 obj <>stream application/pdf Fabrication and Characterization ofNanoCalcium Sulfate and Human PlateletLysate as a Growth Factor Delivery System Nanocalcium sulfate represents a novel scaffold with enhanced physical properties. The reported advantages of using nanomaterials over conventional size constructs for fabricating functional scaffold/growth-factor delivery systems are based on their increased surface area for growth factor adsorption and cell attachment. Recent reports on human platelet lysate suggest that it is a reliable source of osteogenic growth factors and is capable of potentiating robust increases in the activity of osteogenic cells To gain more insight on the advantages of fabricating nanomaterials with growth factors, it is important to determine the amount of growth factor content being released and whether or not it is still biologically active. Treating nanomaterials with growth factors may give rise to novel regenerative micro/nano-environments that could be useful for bone tissue engineering applications. © 2016 Dziak R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Andrew Barone Adam Morrell and Rosemary Dziak* Nano calcium sulfate Human platelet lysate Platelet-derived growth factor Mesenchymal stem cells Human osteoblastic cells 2016-07-02T12:46:43+05:30 2016-07-02T12:46:48+05:30 2016-07-02T12:46:48+05:30 5 Adobe InDesign CS6 (Windows) uuid:63ec9338-84d2-478d-98c9-8d21c669d7d5 xmp.did:FE00469DB0C7E411AEB789ACBE3823B3 xmp.id:E583B3E62440E611A25CD65F6385D73C proof:pdf xmp.iid:E483B3E62440E611A25CD65F6385D73C xmp.did:F2BC7D9EC6C7E411AEB789ACBE3823B3 xmp.did:FE00469DB0C7E411AEB789ACBE3823B3 default converted from application/x-indesign to application/pdf Adobe InDesign CS6 (Windows) / 2016-07-02T12:46:43+05:30 Citation: Barone A, Morrell A, Dziak R (2016) Fabrication and Characterization of NanoCalciumSulfate and Human Platelet Lysate as a GrowthFactor Delivery System. Int J Dent Oral Health2(4): http://dx.doi.org/10.16966/2378-7090.172 Rosemary Dziak, Department of Oral Biology, University at Buffalo,State University of New York, Buffalo, NY, USA, 14214; Tel: 716-829-3827; Fax: 716-829-3942; E-mail: rdziak@buffalo.edu Adobe PDF Library 10.0.1 False endstream endobj 288 0 obj <> endobj 930 0 obj <>/Metadata 287 0 R/Names 931 0 R/Outlines 239 0 R/PageMode/UseOutlines/Pages 286 0 R/StructTreeRoot 289 0 R/Type/Catalog/ViewerPreferences<>>> endobj xref 0 1 0000000000 65535 f 287 2 0000645058 00000 n 0000652640 00000 n 930 1 0000653887 00000 n trailer <<2630943265F03A40841A32E0F58EEC37>]/Prev 116>> startxref 654089 %%EOF